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BackgroundLaparoscopic surgery has traditionally been contraindicated for the management of gall bladder cancer (GBC). This study was undertaken to determine the safety and feasibility of a laparoscopic radical cholecystectomy (LRC) for GBC and compare it with an open radical cholecystectomy (ORC).
MethodsRetrospective analysis of primary GBC patients (with limited liver infiltration) and incidental...
BackgroundFor resection of colorectal cancer (CRC) liver metastases, pre‐operative portal vein embolization (PVE) is used to increase the size of the future liver remnant (FLR) prior to advanced liver resection when indicated. PVE is speculated to cause tumour progression, but only a limited number of studies have analysed tumour growth after PVE in the context of pre‐procedural chemotherapy, which...
BackgroundThe benefit and timing of radiation therapy (RT) for patients undergoing a resection for pancreatic adenocarcinoma remains unclear. This study identifies trends in the use of radiation over a 10‐year period and factors associated with the use of pre‐operative radiation, in particular.
MethodsThe Surveillance, Epidemiology and End Results registry was used to identify patients aged ≥18 years...
BackgroundLiver surgery for perihilar cholangiocarcinoma (PHC) is associated with high rates of morbidity and mortality.
ObjectivesThis study investigated the impact of low skeletal muscle mass on short‐ and longterm outcomes following hepatectomy for PHC.
MethodsPatients included underwent liver surgery for PHC between 1998 and 2013. Total skeletal muscle mass was measured at the level of the third...
BackgroundDelayed gastric emptying (DGE) is a frequent cause of morbidity, prolonged hospital stay and readmission after a pancreaticoduodenectomy (PD). We sought to evaluate predictive peri‐operative factors for DGE after a PD.
MethodsFour hundred and sixteen consecutive patients who underwent a PD at our tertiary referral centre were identified. Univariate and multivariate (MV) logistic regression...
ObjectivesSurgical resection represents the main curative treatment for giant hepatic haemangioma (GHH). The aim of this study was to compare the respective outcomes of hepatic enucleation (HE) and hepatic resection (HR) for GHH.
MethodsGiant hepatic haemangioma was defined as haemangioma of 5–15 cm in size. A prospectively maintained database consisting of a series of consecutive patients who underwent...
BackgroundThe clinical perspective on hepatic growth is limited. The goal of the present study was to compare hepatic hypertrophy and the kinetic growth rate(KGR) in patients after the ALPPS (Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy) procedure, portal vein embolization (PVE) and living donor liver transplantation.
MethodsVolumetry and KGR of the future liver remnant...
ObjectivePost‐hepatectomy liver failure (PHLF) is the major cause of death following liver resection. The aim of this study was to evaluate the feasibility of an intraoperative simulation of post‐resection liver function.
MethodsIntraoperative liver function was measured by indocyanine green (ICG) clearance using the LiMON™ technology. In 20 patients undergoing anatomic liver resection, ICG plasma...
BackgroundDebate on the optimal mode of preoperative imaging in the management of colorectal liver metastases (CRLM) is ongoing and, despite its longstanding use, the precise role of intraoperative ultrasonography (IOUS) is not well established. This study evaluates the impact of IOUS in the era of high‐quality, cross‐sectional imaging techniques.
MethodsAll patients who underwent liver resection...
BackgroundThe role of hormones in focal nodular hyperplasia (FNH) has been investigated with conflicting results.
ObjectiveThe aim of this study was to evaluate oestrogen and progesterone receptor immunohistochemical expression in FNH and surrounding normal liver (control material).
MethodsBiopsy materials from FNH and control tissue were investigated using an immunostainer. Receptor expression...
IntroductionObstructive jaundice as a result of bile duct tumour thrombus (BDTT) is an unusual clinical entity and an uncommon presenting feature of hepatocellular carcinoma (HCC). This study evaluates the outcome of hepatectomy for HCC with obstructive jaundice as a result of BDTT in non‐cirrhotic livers.
MethodsBetween 1997 and 2012, out of 426 patients with HCC in non‐cirrhotic livers, 39 patients...
ObjectiveTo assess the accuracy of pre‐operative staging in patients with peripheral pancreatic cystic neoplasms (pPCNs).
MethodsFrom 2005 to 2011, 148 patients underwent a pancreatectomy for pPCNs. The pre‐operative examination methods of computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasonography (EUS) were compared for their ability to predict the suggested diagnosis...
BackgroundIn spite of limited evidence demonstrating a benefit, epidural analgesia (EA) is often used for patients undergoing a pancreatectomy. In the present study, the impact of epidural analgesia on post‐operative outcomes after a pancreatectomy is examined.
MethodsUtilizing the Nationwide Inpatient Sample, the effect of EA on peri‐operative outcomes after a pancreatectomy was examined. Multivariable...
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